Agilent 6465B Ultivo Triple Quad LC/MS with ESI Source & 1260 Infinity II Front End
Agilent 6465B Ultivo Triple Quad LC/MS with ESI Source & 1260 Infinity II Front End — a compact, stackable LC/MS/MS paired with a 1260 Infinity II Binary Pump, 1260 Infinity II Multisampler, and Multicolumn Thermostat. Equipped with standard ESI source and VacShield technology. Refurbished and tested by Alliant Scientific.
Listing last updated: September 2026
Description
Agilent 6465B Ultivo Triple Quad LC/MS with ESI Source & 1260 Infinity II Front End Overview
This Agilent 6465B Ultivo Triple Quad LC/MS with ESI Source & 1260 Infinity II Front End pairs the Ultivo’s compact, stackable triple quadrupole design with a complete Infinity II HPLC front end, delivering high-performance LC-MS/MS analysis without the bench space demands of larger comparable systems. The Ultivo eliminates the separate MS footprint by integrating directly into the HPLC stack.
This configuration is equipped with a standard Electrospray Ionization (ESI) source, a proven, versatile ionization technique well suited to a broad range of polar and moderately polar compounds across standard-flow LC-MS/MS workflows. The Ultivo mass spec brings its signature innovations to this configuration — the Vortex Collision Cell for improved ion fragmentation and MRM throughput, the Cyclone Ion Guide for smoother ion transmission, and VacShield technology for capillary changes without venting the system. Using Dynamic MRM, the system can monitor up to 4,000 MRM transitions per run.
This Agilent 6465B Ultivo Triple Quad LC/MS with ESI Source & 1260 Infinity II Front End is offered fully refurbished and tested, in working condition, by Alliant Scientific. Find the instrument’s tune report, verifying performance prior to sale, under Downloads.
Includes:
- Agilent 6465B Ultivo Triple Quad LC/MS
- Electrospray Ionization (ESI) Source
- Agilent 1260 Infinity II Binary Pump (G7112B)
- Agilent 1260 Infinity II Multisampler (G7167A)
- Agilent 1260 Infinity II Multicolumn Thermostat (G7116A)
- Vacuum Pump
- Data System
- 90-Day Warranty
Options:
- Agilent Jet Stream (AJS) Source
Disclaimer: All brand names and trademarks are the property of their respective owners and are used for identification only. We are not an authorized dealer. Software, if included, is not transferable or upgradable.
Looking for a Standalone MS Configuration?
Need just the mass spec without an HPLC front end? See our standalone Agilent 6465B Ultivo with ESI Source, or our Agilent Jet Stream (AJS) configuration with HPLC front end.
Technical Specifications
| Manufacturer | Agilent Technologies |
| MS Model | 6465B Ultivo (G6465B) |
| MS Type | Compact, Stackable Triple Quadrupole LC/MS |
| Ion Source | Electrospray Ionization (ESI) |
| Pump | 1260 Infinity II Binary Pump (G7112B) |
| Autosampler | 1260 Infinity II Multisampler (G7167A) |
| Column Thermostat | 1260 Infinity II Multicolumn Thermostat (G7116A) |
| MRM Capacity | Up to 4,000 transitions (Dynamic MRM) |
| Collision Cell | Vortex Collision Cell |
| Ion Guide | Cyclone Ion Guide |
| Maintenance Feature | VacShield — capillary changes without venting the system |
| Compliance | 21 CFR Part 11 compatible |
| Software | Agilent MassHunter |
| Condition | Refurbished and tested |
| Warranty | 90 days |
Additional information
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Key Features
- Complete LC/MS System
Fully integrated Ultivo MS with 1260 Infinity II HPLC front end. - Standard ESI Source
Proven, versatile electrospray ionization suited to a broad range of polar and moderately polar compounds. - High-Pressure Binary Pump
1260 Infinity II Binary Pump delivers precise, reproducible gradient separations. - Automated Sample Handling
1260 Infinity II Multisampler supports flexible, high-capacity injection. - Vortex Collision Cell
Improves ion fragmentation and transmission for more MRMs per second. - VacShield Technology
Change capillaries without venting the system, reducing downtime.
Applications
- Food Safety Testing
Pesticide and contaminant screening in complex food matrices. - Environmental Studies
Trace organic compound analysis in environmental samples. - Toxicology & Forensics
Compound identification and quantitation for toxicology and forensic casework. - Clinical & Pharmaceutical
Protein quantitation and pharmaceutical compound analysis.
FAQ (Frequently Asked Questions)
What HPLC components are included with this system?
A 1260 Infinity II Binary Pump (G7112B), 1260 Infinity II Multisampler (G7167A), and 1260 Infinity II Multicolumn Thermostat (G7116A).
Why choose ESI over Agilent Jet Stream (AJS)?
Standard ESI is a proven, versatile choice for a wide range of standard-flow LC-MS/MS applications. AJS adds a heated sheath gas design for improved desolvation efficiency at higher flow rates, available as an option on this system.
How many MRM transitions can this system monitor?
Up to 4,000 MRM transitions using Dynamic MRM.
Can I purchase the mass spec without the HPLC front end?
Yes — see our standalone Agilent 6465B Ultivo with ESI Source listing.
Does this unit include a warranty?
Yes — this unit ships with a 90-day warranty.
Agilent 6465B Ultivo Tune Report: Agilent-6465b-Ultivo-Triple-Quad-ESI-Source-Tune-Reports
















