Description
Agilent 6465B Ultivo Triple Quad LC/MS with ESI Source Overview
Agilent 6465B Ultivo Triple Quad LC/MS with ESI Source represents a transformative approach to triple quadrupole mass spectrometry, delivering the fit-for-purpose, rugged LC/MS analysis expected from larger comparable systems at a fraction of their size. It’s a compact, stackable design that eliminates the separate MS footprint entirely by incorporating the mass spectrometer directly into the HPLC stack, maximizing lab bench space without compromising performance.
The system performs MS/MS using three sets of parallel rods (quadrupole, hexapole, quadrupole) — the first quadrupole selects precursor ions, which are fragmented in the hexapole into product ions and separated by the second quadrupole. Using Dynamic MRM, the Ultivo can monitor up to 4,000 MRM transitions in a single run.
This configuration is equipped with a standard Electrospray Ionization (ESI) source, a proven, versatile ionization technique well suited to a broad range of polar and moderately polar compounds across standard-flow LC-MS/MS workflows. Innovations built into the Ultivo include the Vortex Collision Cell for improved ion fragmentation and transmission (enabling more MRMs per second with greater accuracy and confidence), the Cyclone Ion Guide for smoother ion transmission between vacuum zones and better signal quality, and VacShield technology, which allows capillary changes without venting the system — reducing downtime and improving day-to-day lab efficiency. The system is compatible with 1260 Infinity II, 1260 Infinity Prime, or 1290 Infinity II LC stacks.
The Ultivo supports 21 CFR Part 11 compliance, making it well suited for regulated environments, and is used across food safety, environmental, drug discovery, toxicology, forensics, bioanalysis, protein quantitation, clinical, academic, pharmaceutical, and veterinary drug applications.
This Agilent 6465B Ultivo Triple Quad LC/MS with ESI Source is offered fully refurbished and tested, in working condition, by Alliant Scientific. Find the instrument’s tune report, verifying performance prior to sale, under Downloads.
Includes:
- Agilent 6465B Ultivo Triple Quad LC/MS with ESI Source System
- Electrospray Ionization (ESI) Source
- Roughing Pump
- Data System
- 90-Day Warranty
Optional:
- Agilent 1260/1290 Infinity II LC Front End
Disclaimer: All brand names and trademarks are the property of their respective owners and are used for identification only. We are not an authorized dealer. Software, if included, is not transferable or upgradable.
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Looking for higher desolvation efficiency and sensitivity? See our Agilent 6465B Ultivo with Agilent Jet Stream (AJS) Source configuration, or browse our full LC-MS inventory.
