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Waters Acquity UPLC System with SQ Detector

Listing #:LS-006374
Brand:Waters Acquity
Model:186003762 (SQ Detector), 186015001 (Binary Solvent Manager), 186015005 (Sample Manager), 186015020 (Sample Organizer), 186015026 (PDA Detector)
Availability:In Stock
Condition:Refurbished
Warranty:90 Days
Onsite Installation:Available upon request
$29,500.00
In Stock
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This Waters Acquity UPLC/MS System combines a Sample Organizer, PDA Detector, Sample Manager, Column Heater (CH-A), Binary Solvent Manager, and SQ Detector for high-resolution UPLC separations with single quadrupole mass detection. It runs up to 3x faster than conventional HPLC without losing resolution, and the SQ Detector adds mass confirmation across a 2–2048 m/z range. Refurbished and tested by Alliant Scientific.

Listing last updated: August 2026

Description

Waters Acquity UPLC System with SQ Detector Overview

Waters Acquity UPLC System with SQ Detector

This system pairs Waters’ ACQUITY UPLC platform with an SQ Detector for combined UV/PDA and mass spectrometric detection in a single configuration. The sub-2µm particle UPLC design delivers roughly 3x the efficiency of conventional 5µm HPLC columns, with up to 70% higher resolution — meaning more information from more samples in less time.

The Binary Solvent Manager handles high-pressure precision mixing for reproducible gradient runs, while the Sample Manager provides reliable automated sample handling. The Sample Organizer extends onboard capacity well beyond the base configuration, useful for labs running large batch queues. The Column Heater (CH-A) maintains consistent column temperature for reproducible retention times across runs.

The PDA Detector adds simultaneous multi-wavelength UV/Vis detection for spectral confirmation, while the SQ Detector brings single quadrupole mass detection into the same workflow — useful when UV/PDA alone isn’t enough to confirm compound identity. The SQ Detector covers a 2–2048 m/z mass range with scan speeds up to 10,000 Da/s, and supports fast polarity switching and multi-mode ionization for flexible method development.

This Waters Acquity UPLC System with SQ Detector is offered fully refurbished and tested, in working condition by Alliant Scientific.

Includes:

  • Waters Acquity UPLC System with SQ Detector
    • Sample Organizer
    • PDA Detector
    • Sample Manager
    • Column Heater (CH-A)
    • Binary Solvent Manager
    • SQ Detector
  • Vacuum Pump
  • Data System
  • 90-Day Warranty

Optional:

  • Premium Refurbishment with Extended Warranty

Disclaimer: All brand names and trademarks are the property of their respective owners and are used for identification only. We are not an authorized dealer. Software, if included, is not transferable or upgradable.

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Looking for other LC-MS configurations? Browse our full selection of LC-MS systems, including single quadrupole and triple quadrupole platforms.

Technical Specifications

Manufacturer Waters
System Type UPLC with SQ Mass Detection
Components Included Sample Organizer, PDA Detector, Sample Manager, Column Heater (CH-A), Binary Solvent Manager, SQ Detector
Maximum Operating Pressure 103,421 kPa (15,000 psi) up to 1 mL/min; 62,053 kPa (9,000 psi) up to 2 mL/min
Composition Accuracy 0.5% absolute (full scale), 5–95%, 0.50–2.00 mL/min
Sample Capacity (base) Up to 768 samples in two 384-well plates
Sample Capacity (with Sample Organizer) Expandable up to 8,448 samples
PDA Wavelength Range 190–800 nm
SQ Detector Mass Range 2–2,048 m/z
SQ Detector Scan Speed Up to 10,000 Da/s
Ionization Dual orthogonal API source (ZSpray), multi-mode, rapid polarity switching
Condition Refurbished and tested
Warranty 90 days

Additional information

Availability

Condition

Model

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Onsite Installation

Warranty

Brand

Key Features

  • UPLC Speed and Resolution
    Sub-2µm particle technology delivers up to 3x the efficiency and 70% higher resolution than conventional HPLC.
  • Combined UV and Mass Detection
    PDA Detector and SQ Detector together provide spectral and mass confirmation in one workflow.
  • Wide SQ Mass Range
    2–2,048 m/z range with scan speeds up to 10,000 Da/s.
  • Expandable Sample Capacity
    Sample Organizer extends capacity up to 8,448 samples for high-throughput queues.
  • Precision Solvent Delivery
    Binary Solvent Manager ensures reproducible high-pressure gradient mixing.
  • Consistent Column Temperature
    Column Heater (CH-A) maintains stable retention times across runs.

Applications

  • Pharmaceutical Analysis
    Compound identification and quantitation with combined UV/MS confirmation.
  • Method Development
    Flexible ionization and polarity switching support broad method scope.
  • High-Throughput Screening
    Expanded sample capacity suited for large batch queues.
  • Impurity and Purity Analysis
    Spectral and mass data together for confident compound confirmation.

FAQ (Frequently Asked Questions)

What components are included in this Waters Acquity system?

Sample Organizer, PDA Detector, Sample Manager, Column Heater (CH-A), Binary Solvent Manager, and SQ Detector.

What is the mass range of the SQ Detector?

2 to 2,048 m/z, with scan speeds up to 10,000 Da/s.

How much faster is UPLC than conventional HPLC?

Up to 3x faster flow rates without a loss in resolution, thanks to the sub-2µm particle column technology.

What is the sample capacity of this system?

Up to 768 samples in the base configuration (two 384-well plates), expandable to 8,448 samples with the included Sample Organizer.

Does this system include mass spectrometry detection?

Yes — the included SQ Detector adds single quadrupole mass detection alongside the PDA Detector’s UV/Vis spectral detection.

Does this unit include a warranty?

Yes — this unit ships with a 90-day warranty.