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Description
Agilent 6120B Single Quad LC/MS with 1200 HPLC System
Agilent 6120B Single Quad LC/MS with 1200 HPLC System is a versatile analytical platform designed for reliable compound identification and routine quantitative workflows. By integrating liquid chromatography separation with mass spectrometry detection and diode array detection, the system provides a multi-dimensional analytical approach for improved confidence in compound analysis.
The system delivers stable and reproducible chromatographic performance through precise solvent delivery and consistent flow control, supporting gradient-based separations across a wide range of analytical methods. Efficient degassing minimizes baseline noise, while automated sample injection ensures high reproducibility and reduced variability between analyses. In addition to mass detection, the diode array detector (DAD) provides UV-Vis spectral data, allowing additional confirmation of compound identity and peak purity. This dual-detection capability is particularly valuable in applications requiring both qualitative and quantitative validation. The single quadrupole mass spectrometer supports both full scan and Selected Ion Monitoring (SIM), enabling flexibility between unknown screening and targeted compound analysis. With stable ionization and consistent signal performance, the system provides dependable results for routine laboratory use.
This refurbished Agilent 6120B Single Quad LC/MS system has been fully tested and verified to be in proper working condition by Alliant Scientific.
Includes:
- Agilent 6120B Single Quad LC/MS
- Source
- Vacuum Pump
- Agilent 1200 HPLC System
- G1322A Degasser
- G1311A Quat Pump
- G1329B Autosampler
- G1316A TCC
- G1315D DAD
- Data System
- 90 Day Warranty Coverage
Optional:
- Premium refurbishment available with extended warranty options
Disclaimer:Â All brand names and trademarks are the property of their respective owners and are used for identification only. We are not an authorized dealer. Software, if included, is not transferable or upgradable.
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Technical Specifications
- System Type: Single quadrupole LC/MS system with DAD HPLC integration
- Mass Analyzer: Single quadrupole mass spectrometer (Agilent 6120B)
- Scan Modes: Full Scan and Selected Ion Monitoring (SIM)
- Ionization Source: Electrospray ionization (ESI), APCI compatible
- Mass Range: Up to m/z ~3000
- Sensitivity: Optimized for routine qualitative and moderate quantitative analysis
- Pump: Quaternary low-pressure gradient pump (G1311A)
- Flow Rate Range: 0.001 – 10 mL/min
- Degasser: Vacuum degasser (G1322A)
- Autosampler: Automated injection system with low carryover (G1329A)
- Injection Volume Range: ~0.1 – 100 µL
- Column Compartment: Thermostatted column compartment (G1316A)
- Temperature Range: Ambient to ~80°C
- Detector: Diode Array Detector (G1315D)
- Wavelength Range: ~190 – 950 nm
- Automation: Sequence-based batch processing capability
- Power Requirements: 100 – 240 V, 50/60 Hz
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Additional information
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Key Features
- Single Quadrupole Detection: Reliable mass detection for compound identification and routine analysis
- Dual Detection Capability: Combines LC/MS with diode array detection for enhanced compound confirmation
- Quaternary Gradient Control: Supports flexible solvent mixing for diverse analytical methods
- Selective Ion Monitoring (SIM): Improves sensitivity for targeted compound analysis
- Stable Baseline Performance: Degassing reduces noise and improves signal consistency
- High Injection Precision: Autosampler ensures accurate and reproducible sample introduction
- Thermal Stability: Controlled temperature enhances separation reproducibility
- Routine Workflow Efficiency: Designed for reliable daily laboratory operation
Applications
- Pharmaceutical Analysis: Identification of APIs, impurities, and drug compounds
- Bioanalytical Testing: Analysis of compounds in biological samples such as plasma and serum
- Environmental Monitoring: Detection of pesticides, pollutants, and contaminants in water and soil
- Food Safety Testing: Identification of additives, residues, and quality markers
- Chemical Analysis: Characterization of organic compounds and complex mixtures
- Quality Control Laboratories: Routine testing for compliance and product consistency
Frequently Asked Questions (FAQ)
- What is the advantage of a quaternary pump in this system? It allows flexible solvent mixing, making it suitable for a wide range of chromatographic methods and applications.
- Why combine LC/MS with a diode array detector? The DAD provides UV-Vis spectral data for additional compound confirmation and peak purity analysis alongside mass detection.
- What type of analysis is this system best suited for? It is ideal for compound identification, routine screening, and moderate-sensitivity quantitative analysis.
- What is Selected Ion Monitoring (SIM)? SIM improves sensitivity by focusing on specific ions of interest during analysis.
- What types of samples can be analyzed? Pharmaceuticals, environmental samples, food products, and a wide range of organic compounds.
- Is this system suitable for trace-level detection? It is best suited for routine analysis; ultra-trace detection typically requires triple quadrupole systems.
- How does temperature control improve analysis? Stable temperature conditions improve retention time consistency and chromatographic reproducibility.
- Can this system handle high-throughput workflows? Yes, automated sampling enables efficient batch processing.
