Description
This Agilent 6546 QTOF with 1290 Infinity II Front End is a high-throughput accurate-mass system for laboratories that screen large sample sets and need fast, confident identification. The Agilent 6546 QTOF keeps its resolution above 30,000 across the mass range, and above 60,000 at higher masses, even at fast acquisition rates. That combination lets analysts separate compounds with nearly identical masses and assign molecular formulas from accurate fragments.
The 1290 Infinity II front end is what makes the system fast. The binary pump delivers up to 1300 bar at flows to 2 mL/min, so it runs sub-2 µm columns and short gradients, and its low delay volume keeps runs tight. The multisampler holds up to 16 microtiter plates, or 6144 samples, and a sample thermostat keeps them cool during long sequences. A multicolumn thermostat stabilizes retention times, and a diode array detector records UV data at up to 240 Hz beside the mass spectra.
Contract research and testing organizations use this kind of system for high-volume work where turnaround time decides the contract. Pharmaceutical groups run it for drug metabolism studies and metabolite identification, and for extractables and leachables testing of packaging and medical devices. Environmental laboratories use it for non-target PFAS and contaminant screening, and food laboratories rely on it for authenticity testing of olive oil, honey, and juices. Forensic toxicology laboratories screen blood and urine for unknown drugs, and biotech and nutrition companies use it for lipid and metabolite profiling.
This Agilent 6546 QTOF Mass Spectrometer with 1290 Infinity II front end is offered fully refurbished and tested, in working condition, by Alliant Scientific.
Includes:
- Agilent 6546 QTOF Mass Spectrometer
- G1958-65271 Jet Stream (AJS) Dual Spray ESI Source
- Agilent 1290 Infinity II HPLC System
- G7120A High-Speed Pump
- G7167B Multisampler
- G7167-60101 Sample Thermostat
- G7116B Multicolumn Thermostat (MCT)
- G7117B Diode Array Detector (DAD)
- G3215A Mass Spectrometer Bench
- MS40+ Rotary Vane Roughing Pump
- Dell PC with Windows 11 Pro and Data System
- 90-Day Warranty
Compare Agilent 6546 Systems
Compare this system with the Agilent 6546A Q-TOF LC/MS System with 1260 Infinity II Front End, which pairs the same mass spectrometer with a variable wavelength detector at a lower entry point.
Disclaimer: All brand names and trademarks are the property of their respective owners and are used for identification only. The seller is not authorized by or associated with Agilent. This product has not been reviewed, tested, or certified by Agilent to verify its quality or compatibility with Agilent’s products. Software, if included, is not transferable or upgradable.
Listing last updated: November 2026.










