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Agilent 6550 iFunnel Q-TOF LC/MS

Listing #:LS-004849
Brand:Agilent
Model:6550
Availability:In Stock
Condition:Refurbished
Warranty:90 Days
Onsite Installation:Available upon request
$69,000.00
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Agilent 6550 iFunnel Q-TOF LC/MS — Agilent 6550 iFunnel Q-TOF LC/MS — up to 42,000 FWHM resolution with femtogram-level sensitivity via iFunnel ion focusing technology. Refurbished and tested by Alliant Scientific.

Description

Agilent 6550 iFunnel Q-TOF LC/MS Overview

The Agilent 6550 iFunnel Q-TOF LC/MS is a high-resolution, accurate-mass mass spectrometer built around Agilent’s iFunnel ion-focusing technology. iFunnel combines Jet Stream thermal gradient focusing, a hexabore sampling capillary, and a dual-stage ion funnel to deliver femtogram-level detection sensitivity.

Ion Beam Compression and Shaping (IBCS) technology compresses and cools the ion beam up to 10-fold, delivering up to 42,000 FWHM resolution (m/z 2,722) alongside sub-1-ppm mass accuracy. This combination of resolution and sensitivity makes the 6550 ideal for confident compound identification in complex samples, and it is uncommon in a single benchtop system.

Acquisition speeds reach up to 50 spectra per second in both MS and MS/MS modes, supporting fast UHPLC separations and maximum sampling during data-dependent MS/MS experiments. In-spectrum dynamic range extends up to five orders of magnitude.

The system ships with a Jet Stream ESI source as standard, with APCI and Multimode (ESI/APCI) sources available as options. It’s compatible with Agilent 1260 and 1290 Infinity Series UHPLC front ends — browse our full HPLC inventory to pair a front end with this system.

This Agilent 6550 iFunnel Q-TOF LC/MS is offered fully refurbished and tested, in working condition, by Alliant Scientific.

Includes:

  • Agilent 6550 iFunnel Q-TOF LC/MS
    • Jet Stream Electrospray Ionization (ESI) Source
    • Integrated Time-of-Flight (Q-TOF) Analyzer
    • Two (2) Vacuum Pumps
  • Dell PC with Windows 11 Pro and Data System
  • Warranty Coverage

 

Listing last updated: October 2026.

Technical Specifications

 

Manufacturer Agilent Technologies
Model 6550 iFunnel Q-TOF (G6550A)
Analyzer Type Quadrupole Time-of-Flight (Q-TOF)
Technology iFunnel Ion Source with Jet Stream ESI
MS Mass Range m/z 100 to 10,000
Extended Mass Range m/z 50 to 1,700, or up to 3,200 (mode-dependent)
Quadrupole Mass Range Up to m/z 4,000
Resolving Power 25,000 FWHM at m/z 322; 42,000 FWHM at m/z 2,722
Mass Accuracy (MS) < 1 ppm RMS with internal mass correction
Mass Accuracy (MS/MS) < 2 ppm RMS
Sensitivity specification 1 pg reserpine on-column (standard test condition). iFunnel ion optics enable femtogram-level detection for many compounds.
MS Sensitivity 1 pg reserpine, S/N ~1,000:1
MS/MS Sensitivity 1 pg reserpine, S/N up to ~4,500:1 (max sensitivity mode)
Dynamic Range Up to 5 orders of magnitude (in-spectrum)
Acquisition Rate Up to 50 spectra/second (MS and MS/MS)
Polarity Switching ~1.5 second full cycle
Standard Source Agilent Jet Stream ESI with iFunnel
Optional Sources APCI, Multimode (ESI/APCI), GC-APCI
LC Compatibility Agilent 1260 & 1290 Infinity Series, UHPLC
Flight Tube INVAR-stabilized TOF for thermal stability
Digitizer 4 GHz high-speed digitizer
Software Agilent MassHunter Workstation
Condition Refurbished and tested
Warranty 90 days

Additional information

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Key Features

  • iFunnel Ion Focusing
    Combines Jet Stream thermal gradient focusing, a hexabore capillary, and a dual-stage ion funnel for femtogram-level sensitivity.
  • High Resolution, High Sensitivity
    IBCS technology delivers up to 42,000 FWHM resolution (m/z 2,722) alongside sub-1-ppm mass accuracy.
  • Fast Acquisition
    Up to 50 spectra/second in MS and MS/MS modes for fast UHPLC separations.
  • Wide Dynamic Range
    Up to 5 orders of magnitude in-spectrum, detecting trace analytes alongside high-abundance compounds.
  • Flexible Ion Source Options
    Standard Jet Stream ESI, with APCI, Multimode, and GC-APCI available as options.

Applications

  • Metabolomics & Metabolite ID
    High-resolution, accurate-mass profiling of complex biological samples.
  • Proteomics
    High precursor abundance supports fast-duty-cycle fragmentation for protein/peptide research.
  • Pharmaceutical & Biopharmaceutical Analysis
    Compound identification, impurity profiling, and structural elucidation.
  • Food Safety Testing
    Trace-level contaminant and adulterant screening.
  • Forensics & Toxicology
    Femtogram-level detection for trace compound identification.
  • Environmental Analysis
    Non-target screening of environmental contaminants.

FAQ (Frequently Asked Questions)

What is iFunnel technology?

iFunnel combines Jet Stream thermal gradient focusing, a hexabore sampling capillary, and a dual-stage ion funnel to increase ion transmission, enabling femtogram-level detection sensitivity.

What mass resolution does this system achieve?

The 6550 delivers 25,000 FWHM resolution at m/z 322, rising to 42,000 FWHM at m/z 2,722, giving clean separation of closely spaced ions for confident compound identification.

Does this listing include an LC front end?

No — this is the mass spectrometer only. Agilent 1260 or 1290 Infinity Series UHPLC front ends are available as an option.

What ion sources are available?

Jet Stream ESI ships as standard. APCI, Multimode (ESI/APCI), and GC-APCI are available as options.

Does this unit include a warranty?

Yes — this unit ships with a 90-day warranty.