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Description
Waters Acquity UPLC H-Class System Overview
The WatersACQUITY UPLC H-Class System is an ultra-performance liquid chromatography system designed to perform high-resolution separations, quantitative analysis, and compound identification across a wide range of sample types. Equipped with a Quaternary Solvent Manager, it enables precise blending of multiple mobile phases, supporting both gradient and isocratic methods as well as straightforward transfer of existing HPLC workflows.
The Sample Manager-FTN provides accurate, low-carryover injections, making it suitable for trace-level analysis and high-throughput sample processing. A Column Heater (CH-A) maintains controlled thermal conditions to ensure consistent retention times and improved separation efficiency, while the Photodiode Array (PDA) Detector captures full UV/Vis spectra for peak identification, purity assessment, and detection of co-eluting compounds.
This system is commonly used in pharmaceutical analysis, environmental testing, food safety, and research laboratories, where reliable separation performance, reproducibility, and method flexibility are essential. It is particularly well-suited for applications involving complex sample matrices and regulated workflows requiring accurate, consistent analytical results.
This Waters Acquity UPLC H-Class System is offered fully refurbished and tested, in working condition.
Includes:
- Waters Acquity UPLC H-Class System
- Acquity PDA Detector
- Acquity CH-A Column Heater
- Acquity H-Class Sample Manager-FTN
- Acquity H-Class Quaternary Solvent Manager
- Computer loaded with Data System
- 90-Day Warranty Coverage
Disclaimer:Â All brand names and trademarks are the property of their respective owners and are used for identification only. We are not an authorized dealer. Software, if included, is not transferable or upgradable.
Technical Specifications
| General | |
|---|---|
| System Type | Ultra Performance Liquid Chromatography (UPLC) |
| Configuration | Quaternary system with PDA detector, Sample Manager-FTN, and Column Heater (CH-A) |
| Application | High-resolution separation and analytical detection |
| Solvent Management | |
| Solvent Capacity | Up to 4 mobile phases |
| Flow Type | Quaternary gradient and isocratic operation |
| Sample Manager (FTN) | |
| Injection Type | Flow-through needle |
| Performance | Low carryover, high precision injections |
| Column Heater (CH-A) | |
| Function | Temperature-controlled column environment |
| Benefit | Improved reproducibility and retention time stability |
| PDA Detector | |
| Type | Photodiode Array (UV/Vis) |
| Capability | Full spectral data acquisition and peak analysis |
| Physical | |
| Design | Modular bench-top system |
| Operation | Continuous use in laboratory environments |
Additional information
| Availability | |
|---|---|
| Brand | |
| Condition | |
| Model | |
| Onsite Installation | |
| Warranty |
Key Features
- Quaternary Solvent Management: Enables accurate blending of up to four solvents for gradient and isocratic separations.
- Sample Manager-FTN: Provides precise injections with reduced carryover for reproducible results.
- Column Heater (CH-A): Maintains stable temperature conditions for consistent retention times.
- PDA Detector: Captures full UV/Vis spectra for compound identification and peak purity analysis.
- Low Dispersion Fluidics: Improves peak shape, sensitivity, and overall chromatographic performance.
- Method Transfer Capability: Supports seamless transition from traditional HPLC methods to UPLC.
- Modular Design: Allows flexible configuration and integration within laboratory workflows.
Applications
- Pharmaceutical analysis and method development
- Environmental testing for trace contaminants
- Food and beverage quality control
- Biotechnology and life science research
- Chemical and petrochemical analysis
- Academic and laboratory research
- Quality control and routine analytical testing
Frequently Asked Questions
What is the ACQUITY UPLC H-Class System used for?
The system is used for high-resolution chromatographic separations, quantitative analysis, and compound identification in pharmaceutical, environmental, food safety, and research laboratories.
What makes the H-Class system different from traditional HPLC systems?
The H-Class system provides higher resolution, improved sensitivity, and faster analysis while maintaining quaternary solvent flexibility, making it ideal for transferring existing HPLC methods to a UPLC platform.
What does the quaternary solvent manager do?
The quaternary solvent manager blends up to four mobile phases with high precision, allowing complex gradient methods and increased method versatility.
How does the Sample Manager-FTN improve analysis?
The flow-through needle design reduces sample carryover and ensures accurate, repeatable injections, which is essential for trace-level and high-throughput applications.
What is the role of the PDA detector?
The PDA detector collects full UV/Vis spectral data across each peak, enabling compound identification, peak purity analysis, and detection of co-eluting substances.
Why is column temperature control important?
Maintaining a stable column temperature improves retention time consistency, enhances separation efficiency, and ensures reproducible analytical results.
Which industries commonly use this system?
The system is widely used in pharmaceutical development, environmental testing, food and beverage analysis, and academic research labs where precise and reliable chromatographic data is required.
