Biotage ELSD-A120 Evaporative Light Scattering Detector
The Biotage ELSD-A120 is an evaporative light scattering detector for HPLC and flash chromatography workflows, detecting non-volatile compounds that lack UV absorbance. It uses a Class 1 LED light source and PMT detection with digital signal processing. This unit is refurbished and tested by Alliant Scientific.
Listing last updated: August 2026
Description
Biotage ELSD-A120 Evaporative Light Scattering Detector Overview
The ELSD-A120 detects compounds by nebulizing the column effluent, evaporating the mobile phase, and measuring light scattered by the remaining analyte particles. This makes it effective for detecting non-volatile compounds that lack UV chromophores — including sugars, lipids, surfactants, and other non-UV-active analytes that conventional UV detectors miss.
It uses a 480nm Class 1 LED light source paired with PMT detection and digital signal processing for stable, low-noise output. The nebulizer and evaporator temperatures are independently adjustable, and gas flow is controlled with automatic shut-off for safer, more consistent operation across different solvent systems.
Biotage ELSD-A120 Evaporative Light Scattering Detector is commonly paired with Biotage flash chromatography systems for compound purification and detection, but also integrates into standard HPLC workflows for pharmaceutical, natural products, and general lab analysis where non-UV detection is required.
This Biotage ELSD-A120 is offered fully refurbished and tested, in working condition by Alliant Scientific.
Includes:
- Biotage ELSD-A120 Evaporative Light Scattering Detector
- 30-Day Warranty
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Technical Specifications
| Manufacturer | Biotage |
| Model | ELSD-A120 |
| Detector Type | Evaporative Light Scattering Detector (ELSD) |
| Light Source | 480nm LED (Class 1 LED Product) |
| Detection Method | PMT with digital signal processing |
| Nebulizer Temperature Range | OFF, 25–90°C |
| Evaporator Temperature Range | OFF, 25–120°C |
| Gas Flow Range | 0.9–3.25 SLM (controlled gas shut-off) |
| Short Term Noise | <0.2mV under specified conditions |
| Installation Category | Category II, indoor use only |
| Operating Altitude | Up to 2000m (6562 ft) |
| Compatible Systems | Biotage flash chromatography, standard HPLC |
| Condition | Refurbished and tested |
| Warranty | 30 days |
Additional information
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Key Features
- Universal Non-UV Detection
Detects compounds lacking UV chromophores, including sugars, lipids, and surfactants. - LED Light Source
480nm Class 1 LED provides stable, low-maintenance illumination. - PMT Detection with Digital Signal Processing
Delivers low-noise, stable output for reliable quantitation. - Adjustable Nebulizer & Evaporator Temperatures
Independently tunable for different solvent systems and analyte classes. - Controlled Gas Flow with Auto Shut-Off
0.9–3.25 SLM range with automatic gas shut-off for safer operation. - Flash Chromatography Compatible
Integrates with Biotage flash systems as well as standard HPLC setups.
Applications
- Flash Chromatography Purification
Pairs with Biotage flash systems for compound purification and detection. - Non-UV Compound Detection
Detects sugars, lipids, surfactants, and other non-chromophoric analytes. - Pharmaceutical Development
Supports purity analysis and compound detection in drug development workflows. - Natural Product Isolation
Suited for isolating and detecting compounds in natural product research.
FAQ (Frequently Asked Questions)
What is the Biotage ELSD-A120 used for?
It’s an evaporative light scattering detector used to detect non-volatile compounds that lack UV absorbance, commonly paired with flash chromatography or HPLC systems.
What light source does the ELSD-A120 use?
A 480nm Class 1 LED light source paired with PMT detection and digital signal processing.
Is the ELSD-A120 compatible with standard HPLC systems?
Yes — while commonly paired with Biotage flash chromatography systems, it also integrates into standard HPLC workflows.
What is the temperature range for the nebulizer and evaporator?
Nebulizer: OFF, 25–90°C. Evaporator: OFF, 25–120°C — independently adjustable for different solvent systems.
Does this unit include a warranty?
Yes — this unit ships with a 30-day warranty.










