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Description
This Agilent 6460A Triple Quad LC/MS System is engineered for high‑sensitivity, targeted quantitative analysis across a wide range of complex sample types. It excels in workflows that require precise detection of trace‑level contaminants, regulated compounds, and small‑molecule analytes. Common applications include environmental monitoring of pesticides, PFAS, pharmaceuticals, and emerging contaminants; food and beverage safety testing for residues, toxins, and adulterants; pharmaceutical and biopharma quantitation for PK studies, impurity profiling, and biomarker analysis; and clinical or forensic research requiring accurate, reproducible mass‑spectrometric measurements. Its stability, sensitivity, and robust quantitative performance make it a trusted platform for routine testing, regulatory compliance, and advanced analytical method development.
Includes:
- Agilent 6460A Triple Quad LC/MSÂ
- Agilent G1958-65138 Jet Stream SourceÂ
- Agilent 1260 Infinity Front EndÂ
- Degasser
- Binary Pump
- AutosamplerÂ
- TCC
- Vacuum PumpÂ
- Dell Windows 11 PC loaded with Data System
- Warranty Coverage
Optional:
- Premium refurbishment available with extended warranty options
Disclaimer:Â All brand names and trademarks are the property of their respective owners and are used for identification only. We are not an authorized dealer. Software, if included, is not transferable or upgradable.
Specifications — Agilent 6460A Triple Quadrupole LC/MS System
Mass Spectrometer
- Type: Triple Quadrupole LC/MS
- Mass Range: m/z 5–2,000
- Scan Modes: MRM, Dynamic MRM, SIM, Product Ion, Precursor Ion, Neutral Loss
- Polarity: Fast polarity switching (+/–)
- Sensitivity: Low‑fg to pg‑level quantitation depending on analyte
- Resolution: Unit mass resolution on all quadrupoles
- Collision Cell: High‑efficiency hexapole collision cell
- Ion Optics: Agilent iFunnel technology (if equipped)
Ion Source (Jet Stream)
- Ionization: ESI with Jet Stream thermal focusing
- Nebulizer Gas: Nitrogen
- Drying Gas Temperature: Up to 350–400°C
- Sheath Gas Temperature: Up to 350–400°C
- Enhanced sensitivity for trace‑level quantitation
LC Front End (1260 Infinity Series)
- Flow Range (Binary Pump): 0.001–5 mL/min
- Pressure Rating: Up to 600 bar
- Autosampler Precision: <0.25% RSD
- Injection Volume: 0.1–100 µL (model‑dependent)
- TCC Temperature Range: Ambient +10°C to 80°C
- Degassing: 4‑channel vacuum degasser
Vacuum System
- Pump Type: Oil‑sealed rotary vane or dry pump (model varies)
- Supports high‑throughput MS operation with stable vacuum levels
Applications
- Targeted Quantitative Analysis Ideal for high‑precision quantitation of trace‑level compounds in complex matrices, supporting workflows that require low detection limits and high reproducibility.
- Environmental Testing Used for monitoring pesticides, herbicides, PFAS, pharmaceuticals, and other contaminants in water, soil, and air samples under EPA‑regulated methods.
- Food & Beverage Safety Supports detection of veterinary drug residues, mycotoxins, allergens, adulterants, and process contaminants with high accuracy.
- Pharmaceutical & Biopharma Enables bioanalysis, pharmacokinetics, impurity profiling, and targeted biomarker quantitation in drug development and QC environments.
- Clinical & Toxicology Research Suitable for quantifying metabolites, hormones, drugs of abuse, and therapeutic compounds in biological matrices.
- Forensic & Public Health Applied in toxicology screening, confirmatory testing, and trace‑level detection of controlled substances and emerging threats.
- Chemical & Materials Analysis Supports characterization of additives, degradation products, and small molecules in industrial and research settings.
Additional information
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